The Class III biological safety cabinet provides an absolute level of safety, which cannot be attained with Class I and Class II cabinets.All Class III cabinets are usually made of welded metal construction and are designed to be gas tight and work is performed through glove ports in the front of the cabinet.During routine operation, negative pressure relative to the ambient environment is maintained within the cabinet which provides an additional fail-safe mechanism in case physical containment is compromised.
On all Class III cabinets, exhaust air is HEPA-filtered and incinerated.Materials are transferred into the cabinet using a pass-through unit installed at the side of the work area.
Class III cabinets usually exhaust air back to the laboratory!however, air may also be exhausted via a dedicated ductwork system to the external environment.When a dedicated ductwork system is employed, they are also suitable for work employing toxic chemicals as an adjunct to microbiological processes.
Must-have features to consider:
- Dual exhaust ULPA filters provides better protection than single-stage designs
- User-friendly control system
- Single piece, leak-tested Neoprene™ gauntlets to guarantee maximum protection.
- Integrated pass-through with interlocking doors permits materials transfer without risk of environmental contamination.
- Angled cabinet front ensures a comfortable working posture.
- Magnehelic gauge mounted on the rear of work zone for easy monitoring
- Audible and visual alarms to notify user of unsafe condition
- Isocide™ powder coat that inhibits microbial growth
Sentinel™ Silver Microprocessor Controllerhas one-line LCD screen for display of airflow status and time.There are soft touch keys for fan, lamp, socket, and UV lamp.The cabinet will signal audible and visual alarms during unwanted events.
Sentinel™ Gold Microprocessor Controllerhas four-line LCD screen for simultaneous display of airflow status, airflow velocity, socket, sash, cabinet model, and time.There are soft touch keys for blower, light, and UV lamp.The cabinet will signal audible and visual alarms during unwanted events.
HMI Control Systemsupervises all functions and monitors cabinet performance in real time.It has a large graphical LCD to illustrate isolator operating parameters.Alarm package is available for users with more sophisticated requirements.
AC3-4B
Airstream®Class III Biological Safety Cabinet
Specifications:
- Dual exhaust ULPA Filter
- Negative pressure work zone
- Monitored by a Magnehelic™ gauge
- Sentinel™ Silver Microprocessor controller
- Single piece, leak-tested Neoprene™ gauntlets
- Ergonomically angled front
- Available sizes: 4 ft, 5 ft, and 6 ft
CBI III
Containment Barrier Isolators (CBI)
Specifications:
- Double-filtered exhaust air via ULPA filters
- Single-piece and leak-tested glove assemblies for maximum protection
- Fully welded stainless steel 316L (internal chambers) and 304 (external housing)
- Suitable for handling Biosafety Levels 1 to 4
- Available sizes: 4ft, 5ft, and 6ft.
SCI III
Streamline® Containment Isolator - Class III
Specifications:
- ISO Class 3 work zone
- Superior operator protection for cytotoxic drug handling
- Fast purging time
- Motorized height stand
- Suitable for cytotoxic drug handling
- Available sizes: 4ft and 6ft
TFAI III
Turbulent Flow Aseptic Isolator (TFAI)™
Specifications:
- Automated airflow and pressure control
- LED lamps for superior illumination
- Oval-shaped glove ports to maximize arm movement
- Hydraulic support frame legs for operator comfort
- Suitable for hazardous or non-hazardous drug handling
- Available sizes: 4ft, 5ft, and 6ft.
All Class III biological safety cabinets are suitable for work with microbiological agents assigned to biosafety levels 1, 2, 3 and 4.These BSCs are frequently specified for work involving the most lethal biological hazards.
Class III BSC may be used with or without a ducting system.Due to the nature of work that is typically conducted in a Class III BSC, ducting the biosafety cabinet provides an additional layer of protection.Installing a ducting system means that there is no recirculation of air inside the laboratory keeping the operators and environment safer from biohazards.
Biosafety cabinets is an airflow containment device designed for handling biohazardous agents.BSCs provide sample, personnel, and environment protection.Typically, EN12469 and NSF 49 are the standards used as references.Isolators are containment devices for sterile drug compounding that offers product protection.Isolators are designed with negative pressure to provide personnel and environment protection.USP 797 is used as the guiding principle for isolators.
No, the gloves are not autoclaveable.When cleaning or disinfecting the gloves of Airstream® Class III Biosafety Cabinet, Esco recommends the use of 70% isopropyl alcohol.
The front glass of Airstream® Class III Biosafety Cabinet is constructed from 8 mm tempered glass.Tempered glass is a type of safety glass processed by controlled thermal or chemical treatments to increase its strength compared with normal glass.Tempering creates balanced internal stresses which cause the glass, when broken, to crumble into small granular chunks instead of splintering into jagged shards.This property makes tempered glass safer and likely to cause lesser injuries.
a.The blower static pressure needed / how many Horse Powers of the blower needed = 150 pascal, recommended exhaust fan PP025 0.34kw (0.5 HP) b.The recommended flow rate = 603 cmh c.The recommended diameter of duct to be used = 8 inch round duct.d.The structural loading and electrical connections should be sufficient for AC3 requirements.e.The biosafety cabinet should be subjected to gaseous decontamination prior to moving it to the new location.f.The biosafety cabinet should be re-certified after installation in the new site is completed.Risk assessment is strongly recommended prior to any relocation to ensure hazards are reasonably identified, risk evaluated, and all issues are mitigated accordingly.
The Airstream® Class III Biosafety Cabinet (AC3) is builty with safety in mind.It features: An air-tight design - completely welded construction to ensure absolute containment for operator and environmental safety Dual exhaust ULPA filter - which creates a ISO Class 3 workzon and offers 10 x better filtration efficiency compared to HEPA Magnehelic pressure gauge - mounted at the rear zone for easy monitoring
Airstream® Class III Biosafety Cabinet (AC3) uses a microprocessor-based control system.It supervises all cabinet functions and has a large display of the cabinet's parameters.The control system also features easy-to-use keypads.
Yes, Airstream® Class III Biosafety Cabinet (AC3) complies to EN 12469 requirements.
Yes, Airstream® Class III Biosafety Cabinet (AC3) is equipped with a disposable and non-washable polyester fiber pre-filter with 85% arrestance / EU3 rated.
The estimated shelf life of HEPA or ULPA filters is up to 10 years when stored properly.
Filters should be kept in their original packaging and should not be exposed to dampness, excessive heat, cold or rapidly changing temperatures.These filters can tolerate up to 95% humidity!anything higher can cause the filter media to block and fail.